Treatment Resistant Depression – FDA Approved Treatment with Spravato

Treatment-resistant depression occurs when individuals do not experience adequate improvement from at least two traditional antidepressant medications. At Private Mental Health Group LLC, we offer FDA-approved treatment using intranasal esketamine (Spravato) for adults who qualify. This advanced therapy targets different receptors in the brain than standard antidepressants, providing new hope and faster relief for those who continue to struggle with persistent depressive symptoms.

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Spravato is administered as a nasal spray in our clinic under direct medical supervision. The medication is absorbed quickly and begins affecting brain activity within hours, helping restore mood-related neurotransmitter balance and improve communication between nerve cells. Many patients experience a reduction in depressive symptoms sooner than they would from traditional options alone.

Our team ensures a safe and supportive experience throughout each session. After receiving Spravato, patients remain in a private observation area for approximately two hours while providers monitor progress and comfort. Treatment plans are individualized and often combined with psychotherapy or ongoing medication management to support sustained mental health improvement.

If you have not found relief with previous antidepressants, Spravato therapy may be an effective next step.

Frequently Asked Questions

What is Spravato?

Spravato (esketamine) is an FDA-approved nasal spray medication used specifically for adults with treatment-resistant depression.

How does it differ from traditional antidepressants?

Spravato works through NMDA receptor pathways in the brain instead of serotonin-based mechanisms, helping restore mood function more rapidly.

Is Spravato safe?

Yes. It is administered only in certified clinical settings under provider supervision to ensure patient safety throughout treatment.

How soon will I feel results?

Some patients experience meaningful symptom improvement within hours to days, though results vary by individual.

Is Spravato covered by insurance?

Many insurance providers offer coverage for treatment-resistant depression. Our team assists with verification and authorization.